Journal
Mitra, R., Fitzsimons, HL., Hale, T., Tan, ST., Gray, C., & White, MPJ. (2024). Recent advances in understanding the molecular basis of infantile haemangioma development.
British Journal of Dermatology. Advance access publication, Retrieved from https://academic.oup.com/bjd/advance-article/doi/10.1093/bjd/ljae241/7689274
[Journal article]Authored by: Fitzsimons, H.Read article at Massey Research Online:
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Tan, WJ., Hawley, HR., Wilson, SJ., & Fitzsimons, HL. (2024). Deciphering the roles of subcellular distribution and interactions involving the MEF2 binding region, the ankyrin repeat binding motif and the catalytic site of HDAC4 in Drosophila neuronal morphogenesis.
BMC Biology. 22(1)
[Journal article]Authored by: Fitzsimons, H., Hawley, H.Read article at Massey Research Online:
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Hawley, HR., Roberts, CJ., & Fitzsimons, HL. (2023). Comparison of neuronal GAL4 drivers along with the AGES (auxin-inducible gene expression system) and TARGET (temporal and regional gene expression targeting) systems for fine tuning of neuronal gene expression in Drosophila..
microPublication Biology. , Retrieved from https://www.micropublication.org/journals/biology/micropub-biology-000885
[Journal article]Authored by: Fitzsimons, H., Hawley, H.Read article at Massey Research Online:
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Schwartz, S., Wilson, SJ., Hale, TK., & Fitzsimons, HL. (2023). Ankyrin2 is essential for neuronal morphogenesis and long-term courtship memory in Drosophila.
Molecular Brain. 16(1)
[Journal article]Authored by: Fitzsimons, H., Hale, T.Read article at Massey Research Online:
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Palmer, MJ., & Fitzsimons, H. (2023). Herzog is not required for mushroom body development or courtship learning & memory but is required for eye development in Drosophila melanogaster.
microPublication Biology. , Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9926291/
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Hura, AJ., Hawley, HR., Tan, WJ., Penny, RJ., Jacobsen, JC., & Fitzsimons, HL. (2022). Loss of Drosophila Coq8 results in impaired survival, locomotor deficits and photoreceptor degeneration.
Molecular Brain. 15(1)
[Journal article]Authored by: Fitzsimons, H., Hawley, H.Read article at Massey Research Online:
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Main, P., Tan, WJ., Wheeler, D., & Fitzsimons, HL. (2021). Increased Abundance of Nuclear HDAC4 Impairs Neuronal Development and Long-Term Memory.
Frontiers in Molecular Neuroscience. 14
[Journal article]Authored by: Fitzsimons, H.Read article at Massey Research Online:
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Freymuth, PS., & Fitzsimons, HL. (2017). The ERM protein Moesin is essential for neuronal morphogenesis and long-term memory in Drosophila.
Molecular Brain. 10(1)
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Green, KA., Becker, Y., Tanaka, A., Takemoto, D., Fitzsimons, HL., Seiler, S., . . . Scott, B. (2017). SymB and SymC, two membrane associated proteins, are required for Epichloë festucae hyphal cell–cell fusion and maintenance of a mutualistic interaction with Lolium perenne.
Molecular Microbiology. 103(4), 657-677
[Journal article]Authored by: Fitzsimons, H.Read Online:
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Schwartz, S., Truglio, M., Scott, MJ., & Fitzsimons, HL. (2016). Long-term memory in Drosophila is influenced by histone deacetylase HDAC4 interacting with SUMO-Conjugating enzyme UBC9.
Genetics. 203(3), 1249-1264
[Journal article]Authored by: Fitzsimons, H.Read Online:
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Green, KA., Becker, Y., Fitzsimons, HL., & Scott, B. (2016). An epichloë festucae homologue of MOB3, a component of the stripak complex, is required for the establishment of a mutualistic symbiotic interaction with Lolium perenne.
Molecular Plant Pathology. 17(9), 1480-1492
[Journal article]Authored by: Fitzsimons, H.Read Online:
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Linger, RJ., Belikoff, EJ., Yan, Y., Li, F., Wantuch, HA., Fitzsimons, HL., . . . Scott, MJ. (2016). Towards next generation maggot debridement therapy: Transgenic Lucilia sericata larvae that produce and secrete a human growth factor.
BMC Biotechnology. 16(1)
[Journal article]Authored by: Fitzsimons, H.Read Online:
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Fitzsimons, HL. (2015). The Class IIa histone deacetylase HDAC4 and neuronal function: Nuclear nuisance and cytoplasmic stalwart?.
Neurobiology of Learning and Memory. 123, 149-158
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Fitzsimons, HL., Schwartz, S., Given, FM., & Scott, MJ. (2013). The histone deacetylase HDAC4 regulates long-term memory in Drosophila.
PLoS ONE. 8(12)
[Journal article]Authored by: Fitzsimons, H.Read Online:
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Fitzsimons, HL., & Scott, MJ. (2011). Genetic modulation of Rpd3 expression impairs long-term courtship memory in Drosophila.
PLoS ONE. 6(12)
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Fitzsimons, H. (2010). The molecular basis of memory - a tale of snails and flies: How small model organisms can teach us about the brain.
New Zealand BioScience. 19, 6-14
[Journal article]Authored by: Fitzsimons, H.
Noe, F., Vaghi, V., Balducci, C., Fitzsimons, H., Bland, R., Zardoni, D., . . . Vezzani, A. (2010). Anticonvulsant effects and behavioural outcomes of rAAV serotype 1 vector-mediated neuropeptide y overexpression in rat hippocampus.
Gene Therapy. 17(5), 643-652
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Fitzsimons, HL., Riban, V., Bland, RJ., Wendelken, JL., Sapan, CV., & During, MJ. (2010). Biodistribution and safety assessment of AAV2-GAD following intrasubthalamic injection in the rat.
Journal of Gene Medicine. 12(4), 385-398
[Journal article]Authored by: Fitzsimons, H.Read Online:
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Riban, V., Fitzsimons, HL., & During, MJ. (2009). Gene therapy in epilepsy.
Epilepsia. 50(1), 24-32
[Journal article]Authored by: Fitzsimons, H.Read Online:
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Noé, F., Frasca, A., Balducci, C., Carli, M., Sperk, G., Ferraguti, F., . . . Vezzani, A. (2009). Neuropeptide Y Overexpression Using Recombinant Adenoassociated Viral Vectors.
Neurotherapeutics. 6(2), 300-306
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Franich, NR., Fitzsimons, HL., Fong, DM., Klugmann, M., During, MJ., & Young, D. (2008). AAV vector-mediated RNAi of mutant Huntingtin expression is neuroprotective in a novel genetic rat model of Huntington's disease.
Molecular Therapy. 16(5), 947-956
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Jung, AE., Fitzsimons, HL., Bland, RJ., During, MJ., & Young, D. (2008). HSP70 and constitutively active HSF1 mediate protection against CDCrel-1-mediated toxicity.
Molecular Therapy. 16(6), 1048-1055
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Emborg, ME., Carbon, M., Holden, JE., During, MJ., Ma, Y., Tang, C., . . . Eidelberg, D. (2007). Subthalamic glutamic acid decarboxylase gene therapy: Changes in motor function and cortical metabolism.
Journal of Cerebral Blood Flow and Metabolism. 27(3), 501-509
[Journal article]Authored by: Fitzsimons, H.Read Online:
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Kaplitt, MG., Feigin, A., Tang, C., Fitzsimons, HL., Mattis, P., Lawlor, PA., . . . During, MJ. (2007). Safety and tolerability of gene therapy with an adeno-associated virus (AAV) borne GAD gene for Parkinson's disease: an open label, phase I trial.
Lancet. 369(9579), 2097-2105
[Journal article]Authored by: Fitzsimons, H.Read Abstract:
Fitzsimons, HL., & During, MJ. (2006). Design and Optimization of Expression Cassettes Including Promoter Choice and Regulatory Elements. , 3-16
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Noordmans, AJ., Song, DK., Noordmans, CJ., Garrrity-Moses, M., Fitzsimons, H., During, MJ., . . . Boulis, NM. (2004). Adeno-associated viral glutamate decarboxylase expression in the lateral nucleus of the rat hypothalamus reduces feeding behavior.
Gene Therapy (Basingstoke). 11(9)
[Journal article]Authored by: Fitzsimons, H.
During, MJ., Cao, L., Zuzga, DS., Francis, JS., Fitzsimons, HL., Jiao, X., . . . Haile, CN. (2003). Glucagon-like peptide-1 receptor is involved in learning and neuroprotection.
Nature Medicine. 9(9), 1173-1179
[Journal article]Authored by: Fitzsimons, H.Read Online:
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Luo, J., Kaplitt, MG., Fitzsimons, HL., Zuzga, DS., Liu, Y., Oshinsky, ML., . . . During, MJ. (2002). Subthalamic GAD gene therapy in a Parkinson's disease rat model.
Science. 298(5592), 425-429
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Fitzsimons, HL., Bland, RJ., & During, MJ. (2002). Promoters and regulatory elements that improve adeno-associated virus transgene expression in the brain.
Methods. 28(2), 227-236
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Xu, R., Janson, CG., Mastakov, M., Lawlor, P., Young, D., Mouravlev, A., . . . During, MJ. (2001). Quantitative comparison of expression with adeno-associated virus (AAV-2) brain-specific gene cassettes.
Gene Therapy. 8(17), 1323-1332
[Journal article]Authored by: Fitzsimons, H.Read Online:
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Mastakov, MY., Baer, K., Xu, R., Fitzsimons, H., & During, MJ. (2001). Combined injection of rAAV with mannitol enhances gene expression in the rat brain.
Molecular Therapy. 3(2), 225-232
[Journal article]Authored by: Fitzsimons, H.Read article at Massey Research Online:
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Fitzsimons, HL., McKenzie, JM., & During, MJ. (2001). Insulators coupled to a minimal bidirectional tet cassette for tight regulation of rAAV-mediated gene transfer in the mammalian brain.
Gene Therapy. 8(22), 1675-1681
[Journal article]Authored by: Fitzsimons, H.Read Online:
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During, MJ., Symes, CW., Lawlor, PA., Lin, J., Dunning, J., Fitzsimons, HL., . . . Young, D. (2000). An oral vaccine against NMDAR1 with efficacy in experimental stroke and epilepsy.
Science. 287(5457), 1453-1460
[Journal article]Authored by: Fitzsimons, H.Read Online:
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Fitzsimons, HL., Henry, RA., & Scott, MJ. (1999). Development of an insulated reporter system to search for cis-acting DNA sequences required for dosage compensation in Drosophila.
Genetica. 105(3), 215-226
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Conference
Fitzsimons, HL. (2019, August). HDAC4 on the brain. Presented at
Palmerston North Medical Research Foundation Colloquiu,. Palmerston North.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Fitzsimons, HL. (2019, June). ANKoring HDAC4: investigating molecular mechanisms of memory in Drosophila. Presented at
Genetics Society of Australasia Conference. Melbourne, Australia.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Fitzsimons, H. (2019, December). Investigating nuclear and cytoplasmic roles of HDAC4 in the brain. Presented at
16th Asian Conference on Transcription. Dunedin, New Zealand.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Main, PJ., & Fitzsimons, HL. (2018).
Characterising the subcellular distribution of HDAC4 in Drosophila melanogaster neurological development, learning and memory. Poster session presented at the meeting of 17th European Drosophila Neurobiology Conference. Krakow, Poland
[Conference Poster]Authored by: Fitzsimons, H.
Fitzsimons, H., Freymuth, PS., Main, PJ., & Schwartz, S. (2018).
Investigating the role of the HDAC4-Ankyrin2 interaction in memory formation. Poster session presented at the meeting of 17th European Drosophila Neurobiology Conference (Neurofly). Krakow, Poland
[Conference Poster]Authored by: Fitzsimons, H.
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Fitzsimons, HL. (2017, August). Phenotypic analysis of human ADCK3 mutations in Drosophila. Presented at
Palmerston North Medical Research Foundation Colloquium. Palmerston North, New Zealand.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Green, K., Becker, Y., Tanaka, A., Takemoto, D., Fitzsimons, H., Seiler, S., . . . Scott, B. (2017).
SymB and SymC, two membrane associated proteins, are required for Epichloë festucae hyphal cell-cell fusion and maintenance of a mutualistic interaction with Lolium perenne. Poster session presented at the meeting of 29th Fungal Genetics Conference, Pacific Grove, California. Pacific Grove, United States of America
[Conference Poster]Authored by: Fitzsimons, H.
Green, K., Becker, Y., Tanaka, A., Takemoto, D., Fitzsimons, H., Lalucque, H., . . . Scott, DB. (2016, September). SymB and SymC, two membrane associated proteins, are required for Epichloë festucae hyphal cell-cell fusion and establishment of a mutualistic interaction with Lolium perenne. Presented at
Queenstown Research Week, Plant Molecular Biology Satellite Meeting. Nelson.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Green, K., Becker, Y., Tanaka, A., Fitzsimons, H., Lalucque, H., Silar, P., . . . Scott, B. (2016).
Two Epichloë festucae genes encoding putative membrane associated proteins are required for cell-cell fusion and E. festucae-Lolium perenne symbiosis. Poster session presented at the meeting of 13th European Conference on Fungal Genetics (ECFG13), Paris-La Villette. Paris, France
[Conference Poster]Authored by: Fitzsimons, H.
Fitzsimons, HL., & Freymuth, PS. (2015, August). Moesin - a memory molecule?. Presented at
Palmerston North Medical Research Foundation Colloquium. Palmerston North, New Zealand.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Fitzsimons, HL., Freymuth, PS., & Schwartz, S. (2015, August). HDAC4 and memory formation: Interaction with the actin cytoskeleton. Presented at
Australasian Winter Conference for Brain Research. Queenstown, New Zealand.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Fitzsimons, HL., & Freymuth, PS. (2015).
The actin鈥恇inding protein moesin and memory formation in Drosophila. Poster session presented at the meeting of Australasian Winter Conference for Brain Research. Queenstown, New Zealand
[Conference Poster]Authored by: Fitzsimons, H.
Fitzsimons, HL., & Schwartz, S. (2015).
Investigating the HDAC4 memory pathway: interaction with ankyrin2?. Poster session presented at the meeting of Society for Neuroscience 2015 Annual Meeting. Chicago, United States of America
[Conference Poster]Authored by: Fitzsimons, H.
Fitzsimons, HL., & Schwartz, S. (2014, October). A genetic screen for modifiers of HDAC4. Presented at
2014 European Fly Neurobiology. Crete, Greece.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Fitzsimons, HL. (2014, November). A protein to remember: investigating the role of HDAC4 in memory formation.. Presented at
Genetics Otago Symposium. Dunedin, New Zealand.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Schwartz, S., & Fitzsimons, HL. (2014).
A genetic screen to identify genes that interact with Histone Deacetylase 4 (HDAC4): Investigating the interplay with ankyrin2 in the brain. Poster session presented at the meeting of Australasian Winter Conference for Brain Research
[Conference Poster]Authored by: Fitzsimons, H.
Fitzsimons, HL. (2014, August). Genetic analysis of the role of HDAC4 in long-term memory: interaction with the SUMO-conjugating enzyme Ubc9. Presented at
32nd Australasian Winter Conference on Brain Research. Queenstown, New Zealand.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Fitzsimons, HL. (2013, August). "Regulation of long-term memory formation - the role of histone deacetylases". Presented at
Palmerston North Medical Research Foundation Colloquium. Palmerston North.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Fitzsimons, HL., & Scott MJ, . (2013, February). Genetic analysis of HDAC4 function in long-term memory. Presented at
Australian Neuroscience Society. Melbourne, Australia.
[Conference Oral Presentation]Authored by: Fitzsimons, H.
Fitzsimons, HL. (2011, September). The histone deacetylase Rpd3 regulates long-term courtship memory in Drosophila.. Presented at
Queenstown Research Meeting - Epigenetics Satellite.
[Conference Oral Presentation]Authored by: Fitzsimons, H.